Editorial · pages 13–16
Radiation Oncology and Molecular Biology
Cite this article
The Frontiers Ahead - - Diganta Hazarika, Tejinder Kataria. Radiation Oncology and Molecular Biology. J Int Med Sci Acad. 2005;18(1):13–16.
Opening of the article
Many randomized trials conducted over the last few decades show that combinations of radiation and chemotherapy given concurrently decrease the mortality rate of patients with locally advanced cancers of the head and neck, uterine cervix etc. However, as longer follow up data have become available it has become evident that the survival benefit has been achieved at the expense of increased toxicity and also that a substantial percentage of patients die of their index cancer progression.
Keywords
Signal transduction, epidermal growth factor, farnesyl transferase, Tyrosine kinase. control for some cancers, the phosphatidyl inositol 3’-kinase pathway (PI3-kinase)