Safety and Efficacy of Misoprostol for termation of 1 st and 2 st trimester post cesarean pregnancy

Opening of the article

The purpose of the study was to evaluate the efficacy and safety of PGE1 analogue, misoprostol, for inducing abortion in women who had prior one or more cesarean sections. Women who had to undergo termination of pregnancy between 10 and 22 weeks of gestation for various indications ( missed abortion, fetal anomaly, unwanted pregnancy etc. ) and had at least one previous cesarean section were reviewed over a two year period. Misoprostol 400mcg either vaginally or sublingually every 6hrs (up to maximum 24 hrs ) was the standard regimen for induction of abortion in all cases.