Prevalence of Helicobacter Pylori Infection in Patients with Perforated Duodenal Ulcer: A Hospital-based Study

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Peptic ulcer disease remains the most common cause of gastroduodenal perforation. Among peptic ulcers, it is the duodenal ulcer which commonly perforates. Pyloroduodenal perforation occurs 6-8 times more often than gastric perforations. It is believed that Helicobacter pylori plays an important role in the causation of peptic ulcer. However, its role in duodenal ulcer perforation has not been investigated extensively and the results are conflicting. To determine the prevalence of H. pylori in patients with perforated duodenal ulcer. All the patients admitted over a period of one year with the diagnosis of perforated duodenal ulcer formed the study material.