IMSAInternational Medical Sciences Academy

JIMSA › Vol 34 No 2 · April–June 2021

Original Articles · pages 109–114

Modified Thromboelastography and its Variables: Platelets, Fibrinogen and Erythrocytes. Kesav Jagadeesan, J. Kabalimurthy, K. Ramadevi, N. B. Venkataraman

Cite this article

Modified Thromboelastography and its Variables: Platelets, Fibrinogen and Erythrocytes. Kesav Jagadeesan, J. Kabalimurthy, K. Ramadevi, N. B. Venkataraman. J Int Med Sci Acad. 2021;34(2):109–114.

Opening of the article

Thromboelastography (TEG) has been reported to be useful to detect impaired platelet function in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB), to predict excessive microvascular bleeding (EMB), guide platelet transfusion and administration of desmopressin acetate (DDAVP). As the conventional TEG has a test completion time (TCT) of greater than 30 mins we had earlier reported a modified TEG (TEG-rTT) which was activated by 0.025% of recombinant tissue thromboplastin (rTT) to shorten the TCT to 7 mins. However, TEG-rTT is known to be affected by decrease in concentrations of platelets and coagulation factors including fibrinogen.

Keywords
TEG-rTT, Platelet function, Fibrinogen, RBC, Tissue factor

Published April–June 2021 · Free to read