Drug Utilization Studies of Empirically Prescribed Antimicrobial Agents in Surgical Patients of a Tertiary Care Hospital in Maharashtra, India: An Observational Study

Opening of the article

Introduction: Antibiotic resistance, a threat to the public health, is rapidly increasing worldwide. Irrational and unnecessary antibiotic treatment, contributes to the development of antibiotic resistance. Third-generation cephalosporins are considered the backbone of antibiotic therapy for the treatment of different serious infections, including those in the hospitalized patients. Resistance to them has been increasing rapidly. This drug utilization study was undertaken to understand the growing resistance acquired by the organisms against cephalosporins caused due to the rampant use of cephalosporins in the surgical wards of our institution.