Original Articles · pages 189–194
Spectrum of Hemoglobin Variants: A Cross Sectional Study from North Indian State
Cite this article
Promil Jain, Nisha Marwah, Pinki Devi, Richa Pawar, Arushi Goel, Meenu Gill. Spectrum of Hemoglobin Variants: A Cross Sectional Study from North Indian State. J Int Med Sci Acad. 2021;34(3):189–194.
Opening of the article
Introduction: Hemoglobinopathies, comprising thalassemia syndromes and structural hemoglobin variants are heterogeneous group of inherited monogenic blood disorders, characterized by reduced or absent production of globin chains in hemoglobin. Mutations in genes coding for globin proteins produce thalassemia syndromes and variant hemoglobins. Epidemiologically identification of these disorders are very important to prevent serious clinical implications. Material and Methods: A total of 2518 blood samples of anemic patients were processed by HPLC.
Keywords
Hemoglobinopathies, thalassemia syndromes