Acute Cerebral Venous Sinus Thrombosis after Varicella Infection

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Primary varicella infection is generally a mild disease of childhood. Nowadays it is more commonly seen in adults and sometimes associated with severe complications. The neurological manifestations are mainly in the form of encephalitis, metabolic encephalopathy, seizures and rarely arterial vasculopathy, which cause ischemic strokes, aneurysms, subarachnoid and cerebral haemorrhages. It is also associated with coagulopathy, causing DIC and Purpura fulminans, a severe autoantibody mediated coagulopathy presenting with purpuric or painful necrotizing lesions due to microthrombi in dermal capillaries.