Disseminated Histoplasmosis presented as fever of unknown origin in an adult immuno-competent individual

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Opportunistic infection like Histoplasmosis commonly observed in immunocompromised patients with HIV infection, connective tiss ue disease, organ transplant recipients. Histoplasma, an opportunistic fungus seen in immunocompromised patients, but presents with adrenal gland involvement in immunocompetent individuals. We present the case of an adult immunocompetent patient presenting with fever of unknown origin and was diagnosed with disseminated histoplasmosis with no adrenal involvement.